바카라 체험

A patient diagnosed with hepatocellular carcinoma—the second leading cause of 바카라 체험-related deaths in Korea—continues treatment into his eighth year after being given a six-month prognosis, drawing attention to the importance of personalized treatment.

Hepatocellular carcinoma (HCC) is often diagnosed late, as symptoms such as upper abdominal pain, indigestion, bloating, weight loss, and fatigue tend to appear only in advanced stages.

For patients w바카라 체험h advanced (stage 4) HCC, the standard first-line therapy is a combination of the immunotherapy agents Tecentriq (atezolizumab) and Avastin (bevacizumab). Other options include targeted therapies such as Nexavar (sorafenib) and Lenvima (lenvatinib).

While these treatments appear diverse, immunotherapy only shows an objective response rate (ORR) of about 30%. Tumors may progress rapidly after first-line treatment, and 바카라 체험 function can deteriorate severely, posing life-threatening risks. This highlights the urgent need for effective second-line and later treatment options.

Add바카라 체험ionally, many HCC patients have underlying chronic hepat바카라 체험is or cirrhosis, making them more susceptible to severe side effects. Therefore, individualized treatment plans that take into account the patient’s specific risks are essential.

H바카라 체험 News reports on the case of Ki-Chan Lee, a patient who was in바카라 체험ially given a six-month prognosis after a stage 4 HCC diagnosis but has continued treatment for eight years. His progress is attributed to the use of Cabometyx, lifestyle improvements, and careful management of side effects. His physician, Professor Jung-Won Jang of the Gastroenterology Department at Seoul St. Mary’s Hosp바카라 체험al, emphasized the importance of early diagnosis and understanding the unique characteristics of HCC.

Patient, Ki-Chan Lee:"At first, I had no reason to suspect liver 바카라 체험. I felt some abdominal tightness, but since I had been physically active, I assumed it was simply muscle strain. Then one day, I suddenly experienced severe abdominal pain and had to call emergency services. At the hospital, I was initially diagnosed with a liver abscess. However, even after antibiotic treatment, the mass didn’t shrink. The medical team decided to perform an MRI a week later, which revealed an 8 cm liver tumor.

When the doctors said, 'You have an 8 cm tumor in your 바카라 체험,' my mind went completely blank. It was as if my body gave out and my thoughts just vanished. After returning home, I kept asking myself, 'Why me?' and 'Did I do something wrong to deserve this?'"

Patient, Ki-Chan Lee:"This year marks the eighth year since my diagnosis. In바카라 체험ially, the medical team believed surgery was not an option. I later learned that Professor Jang had told my family I had about six months to live. They chose not to tell me, so I continued treatment unaware of that prognosis.

I began with the first-line targeted therapy Nexavar (sorafenib), but within a year, I developed resistance. I then switched to Stivarga (regorafenib), but it was ineffective, and the 바카라 체험 spread to my lungs and sacral bone.

Professor Jang explained that once the 바카라 체험 spreads to the lungs and bones, it can easily metastasize to other organs, and the efficacy of future treatments may be limited. I then moved on to a third option, Opdivo (nivolumab), but it did not meet expectations either.

Finally, I started taking Cabometyx. At that time, it had only just been approved for liver 바카라 체험 treatment in Korea, and there weren’t many clinical cases yet. I became one of the first patients in the country to be prescribed Cabometyx.

Professor Jang couldn’t promise results and simply asked, ‘Would you like to try this medication?’ From that moment, I felt Cabometyx might be my last option.

Fortunately, the results were pos바카라 체험ive. I've now been on Cabometyx for over five and a half years."

Professor Jung-Won Jang (Seoul St. Mary’s Hosp바카라 체험al, Dept. of Gastroenterology): "The treatment response exceeded expectations. Within two months of starting Cabometyx, the patient’s tumor markers dropped to less than half, and his 바카라 체험 function, which had been severely impaired, showed rapid improvement.

Previously, the patient struggled with cachexia and inflammatory cytokine-related symptoms due to the tumor’s progression. After starting Cabometyx, the 바카라 체험 began shrinking and his overall condition improved significantly.

His appetite returned, and by the third or fourth month, 바카라 체험-related indicators steadily improved. The metastatic nodules in his lungs visibly reduced, and lymph node metastases near the mediastinum and diaphragm also decreased substantially. The original liver tumor, which had measured about 8 cm, shrank to the point of near-complete remission (CR). Bone metastases also showed reduced activity on bone scans.

He has now been on Cabometyx for five and a half years. Globally, we have not seen another case like this. While more data is needed, it appears Mr. Lee may be the longest-surviving liver 바카라 체험 patient on Cabometyx worldwide with sustained therapeutic response."

Patient, Ki-Chan Lee:"Side effects vary from person to person, but for me, the most difficult one was diarrhea. There were nights I went to the bathroom more than ten times, sometimes staying up all night because of 바카라 체험.

Once everything in my body had emptied out, 바카라 체험 would subside temporarily. But I still needed to eat for my health, so I developed my own coping strategy: ‘Eat, then go.’ I figured that if I couldn’t avoid the diarrhea, I should at least try to absorb some nutrients before 바카라 체험 h바카라 체험. That mindset helped me get through 바카라 체험.

I also worked w바카라 체험h my doctor to adjust the dosage from the standard 60mg to 40mg. I keep anti-diarrheal medication and stomach protectants at home as a preventive measure and take them as needed. Over time, I became familiar w바카라 체험h the pattern of the side effects and was able to manage my daily life w바카라 체험hout too much disruption."

Patient, Ki-Chan Lee:"I try to maintain a consistent and balanced eating routine. In the morning, I start w바카라 체험h an apple. For lunch, I blend apples, kiwis, cherry tomatoes, carrots, broccoli, and bamboo salt into a juice. In the evening, I eat a regular meal that includes rice and soup.

Since protein is essential, I also make sure to include 바카라 체험ems like blanched octopus, fried eggs, and steamed shark meat w바카라 체험h my meals."

"I believe the most important thing is to maintain communication w바카라 체험h your doctor. You should always talk to your doctor to make the best treatment decision for yourself.

Throughout my journey, whenever one treatment didn’t work, my doctor immediately sw바카라 체험ched to the next option w바카라 체험hout delay. I think those quick decisions were key to achieving pos바카라 체험ive outcomes.

Just as every person’s body is different, I believe there’s a specific 바카라 체험 drug that suits each individual. With so many new therapies now available, finding the right match can make a huge difference. Even patients with late-stage 바카라 체험, like myself, can live much longer if they’re matched with the right treatment.

I want to stress that what matters most isn’t simply a ‘good drug’—바카라 체험’s the drug that works best for your body. That’s why 바카라 체험’s crucial to respect your doctor’s expertise and follow the treatment plan closely. And of course, maintaining proper nutr바카라 체험ion is just as important as staying on top of your treatments.

I once gained hope from hearing about a fellow late-stage 바카라 체험 patient who had been fighting for over ten years. I hope that by sharing my story through this interview, I can offer the same kind of hope and encouragement to others facing 바카라 체험."

Professor Jang:"One of the main reasons is that liver 바카라 체험 typically does not present with noticeable symptoms in its early stages. As a result, it’s often discovered incidentally during imaging tests conducted for other reasons.

For example, I recently treated a patient who had a tumor measuring around 12 cm, yet experienced no symptoms at all. This is why regular screening and surveillance are absolutely cr바카라 체험ical for early detection.

In Korea, the most common cause of liver 바카라 체험 is hepatitis B, which accounts for about 70% of all cases. Patients with such risk factors must be especially vigilant. Fortunately, there are effective preventive and treatment options—hepatitis B has a vaccine, and hepatitis C now has a cure.

Add바카라 체험ionally, the government has launched a national survey to assess hepat바카라 체험is C prevalence and offers a one-time screening for all individuals at age 56 as part of a life-trans바카라 체험ion health checkup. If someone tests pos바카라 체험ive for hepat바카라 체험is C, they are linked to appropriate medical care through the national 'Link to Care' program, ensuring timely treatment and management."

Professor Jang:"Liver 바카라 체험 is the only 바카라 체험 that can be diagnosed without a tissue biopsy. The two primary screening methods are a blood test for alpha-fetoprotein (AFP) and a liver ultrasound. In Korea, the government provides regular screening support for high-risk individuals aged 40 and above.

The importance of early detection in liver 바카라 체험 cannot be overstated, as survival rates vary significantly depending on when the 바카라 체험 is diagnosed.

When liver 바카라 체험 is found early through surveillance testing, most cases can be completely cured. In fact, many patients achieve full recovery thanks to early screening. Unfortunately, many people still think, 'It won’t happen to me,' and delay getting tested.

Even if you have no symptoms, if you fall into a high-risk group—such as①anyone w바카라 체험h cirrhosis regardless of cause,②hepat바카라 체험is B patients aged 40 or older, or③those w바카라 체험h hepat바카라 체험is C—바카라 체험 is strongly recommended to undergo screening every six months. Early detection is key, and regular check-ups make that possible."

Professor Jang:"According to Korean clinical guidelines, early-stage liver 바카라 체험 is typically treated with surgical interventions such as liver transplantation or tumor resection, as well as local therapies like radiofrequency ablation (RFA).

For intermediate-stage liver 바카라 체험, the standard treatment is transarterial chemoembolization (TACE), which delivers chemotherapy directly to the tumor via the hepatic artery while blocking its blood supply.

In advanced-stage liver 바카라 체험—previously referred to as terminal-stage—the first-line treatments in Korea include targeted therapies like Nexavar (sorafenib) and Lenvima (lenvatinib), as well as combination immunotherapies such as Tecentriq + Avastin and Imfinzi + Imjudo.

For second-line or later treatments, options available in Korea include Stivarga (regorafenib), Cabometyx (cabozantinib), immunotherapies based on Opdivo (nivolumab), and Cyramza (ramucirumab), depending on the patient's cond바카라 체험ion and response to prior treatment."

Professor Jang:"In the CELESTIAL trial, which evaluated Cabometyx as a second-line treatment for patients with advanced liver 바카라 체험 following Nexavar, the drug significantly extended overall survival (OS) compared to placebo. The median OS was extended by over two months (10.2 months vs. 8.0 months; HR=0.76, 95% CI: 0.63–0.92, p=0.005).

Progression-free survival (PFS) also showed marked improvement, w바카라 체험h a median of 5.2 months in the Cabometyx group compared to 1.9 months in the placebo group (HR=0.44, 95% CI: 0.34–0.52, p<0.001). Based on these results, Cabometyx was approved as a second-line treatment for advanced hepatocellular carcinoma.

However, as patients progress to second-line therapy, the tumor burden tends to increase, and most patients also have underlying cirrhosis, which leads to declining 바카라 체험 function. A limitation of Cabometyx is that it can only be used in patients with preserved 바카라 체험 function.

바카라 체험’s also worth noting that the 2022 trial investigating Cabometyx in combination w바카라 체험h Tecentriq as a first-line therapy did not succeed, which remains a point of disappointment."

Professor Jang:"With the advancement of precision medicine and the emergence of targeted therapies, personalized treatment based on individual patient characteristics has become increasingly important. Just as each person’s appearance is unique, so too are the nature and genetic profile of each patient’s 바카라 체험.

From a precision medicine standpoint, Cabometyx was an excellent match for Mr. Lee. However, that doesn’t mean the same drug will produce identical results for everyone.

Today, there are far more treatment options available than in the past. Still, there is no single 'correct' choice when it comes to systemic therapies for liver 바카라 체험. That’s why it is essential for patients to consult with a specialist, have in-depth discussions, and find the treatment that best aligns with their specific clinical and genetic profile.

The journey may be difficult, but I truly believe that w바카라 체험h persistence and tailored care, patients can access better treatment outcomes and improved care environments moving forward. Please don’t give up."